Polynucleotides in Karachi
Regenerative injectables for the under-eye, face, neck and hands. Purified polynucleotides repair the skin from within: thicker, calmer, more hydrated, more even.
Is Polynucleotides right for me?
- For crepey, dark or hollow under-eyes, thin or inflamed skin, acne scarring and early ageing where volume is not the answer.
- Two to three twenty-minute sessions, two to four weeks apart, with small bumps for a day.
- Skin quality improves over two to three months and lasts six to nine months.
Repair, not fill.
Polynucleotides are the regenerative injectable that treats the skin’s health rather than its shape. Purified DNA fragments, derived from salmon, are injected into the skin where they signal fibroblasts to repair, reduce inflammation and produce new collagen and elastin. The skin becomes thicker, better hydrated and more even in tone.
The clinic uses polynucleotides for the under-eye area, where fillers can be risky and the skin is thin and crepey; for the face, neck and hands as a regenerative alternative to skin boosters; for acne scarring and rosacea-prone skin; and, with the hair protocol, for thinning hair.
Two to three sessions, two to four weeks apart, about twenty minutes each. Results build over two to three months.
Where the skin needs repair.
Under-eyes
Thickens thin, crepey lower-lid skin and improves dark circles where filler would be the wrong tool.
Under-eyes → Concern · texture and glowFace
Overall skin health, hydration and tone.
Face → Concern · textureNeck and hands
Crepey, sun-damaged skin.
Neck and hands → Concern · acne and scarsAcne scarring
Supports remodelling alongside microneedling and laser.
Acne scarring → Concern · rednessRosacea-prone skin
Calms inflammation and strengthens the barrier.
Rosacea-prone skin → Concern · hair lossScalp
The hair protocol for thinning.
Scalp →Good candidates
- Under-eye concerns that fillers cannot safely address.
- Thin, inflamed, sensitive or sun-damaged skin.
- Patients who want regeneration rather than volume.
- Preparation for and recovery from laser or microneedling.
Not suitable for
- Fish allergy.
- Pregnancy and breastfeeding.
- Active infection at the injection sites.
- Expectations of volume or lift; polynucleotides improve quality, not shape.
Signal, repair, rebuild.
Mapping
Areas are marked and numbed; the under-eye is treated with a fine cannula or micro-injections.
Injection
Small deposits are placed in the dermis. Twenty minutes for the face.
Regeneration
Fibroblasts are signalled to repair; collagen, elastin and hydration improve over the following weeks. A second and third session build on the first.
From consultation to results.
Twenty minutes after numbing. Small bumps and possible bruising for a day.
The response builds.
Under-eyes brighter and smoother; skin calmer.
Maintenance every six to nine months.
"For the under-eye, polynucleotides are what I use most now. They repair thin skin instead of filling it, and the area looks rested rather than treated."
Consultant Dermatologist and Laser Specialist. Over 35 years of dermatology, trained in Zurich, practising in Clifton since 1999. Page medically reviewed September 2026.
Polynucleotides, answered.
Straight answers from the clinic. If your question is not here, ask on WhatsApp.
Ask on WhatsAppYes. They are highly purified, biocompatible and well tolerated. Bumps, redness or bruising at the sites are the usual, temporary effects. They are not used in fish allergy.
About twenty minutes including numbing.
Small bumps for a few hours and possible bruising for a day or two, especially under the eyes.
Skin looks fresher within two weeks; the full regenerative result develops over two to three months.
Two to three, two to four weeks apart, then maintenance every six to nine months.
Polynucleotides improve the skin quality and darkness; filler adds volume to a hollow. Many under-eyes need quality first, and some need both.
Yes. Injected into the scalp they support follicles and reduce inflammation, as part of the clinic's hair restoration protocols.
Pricing is per session for the course. The clinic shares the exact fee at the consultation. Ask on WhatsApp for current pricing.
Start with a consultation.
A twenty-minute consultation with Dr. Fehmida decides whether this is the right treatment for you, or whether something gentler or stronger would serve you better. Message on WhatsApp or leave your number and the clinic calls you back.
200/1 Clifton 1, Block 5, Clifton, Karachi. Monday to Friday 9:00 to 6:00, Saturday 9:00 to 5:00.
Call or WhatsApp 0301 827 9630